Refinement Recommendations for Intravenous Injection and Body Heat Conservation in Mongolian Gerbils used in SPECT Studies

Authors

  • Christel Palmyre Henri Moons Laboratory for Ethology, Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University
  • Kathelijne Peremans Department of Medical Imaging of Domestic Animals, Faculty of Veterinary Medicine, Ghent University
  • Philippe Büscher Parasite Diagnostics Unit, Department of Parasitology, Institute of Tropical Medicine Antwerp
  • Simon Vermeire Department of Medical Imaging of Domestic Animals, Faculty of Veterinary Medicine, Ghent University
  • Eva Vandermeulen Department of Medical Imaging of Domestic Animals, Faculty of Veterinary Medicine, Ghent University
  • Kurt Audenaert Department of Psychiatry and Medical Psychology, Faculty of Medicine, Ghent University
  • Katleen Hermans Department of Pathology, bacteriology and poultry diseases, Faculty of Veterinary Medicine, Ghent University
  • Frank Olof Ödberg Laboratory for Ethology, Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University

DOI:

https://doi.org/10.23675/sjlas.v35i4.155

Abstract

This paper describes two aspects of Single Photon  Emission Computed Tomography (SPECT) which  have been refined for use in small animals, as  demonstrated by a study on Mongolian gerbils:  intravenous injection of radiotracers in the femoral  vein and body heat conservation in animals  anaesthetized at the time of scanning. Elaborating  on recommendations made by other authors, we  have combined chemical and physical restraint to  optimize injection efficiency as well as to reduce  handling time of the animals. Finally, we provide a  detailed description of a SPECT-compatible waterheated  scanning bed, the application of which we  believe is not limited to scintigraphic studies. 

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Published

01.12.2008

How to Cite

Moons, C. P. H., Peremans, K., Büscher, P., Vermeire, S., Vandermeulen, E., Audenaert, K., Hermans, K., & Ödberg, F. O. (2008). Refinement Recommendations for Intravenous Injection and Body Heat Conservation in Mongolian Gerbils used in SPECT Studies. Scandinavian Journal of Laboratory Animal Science, 35(4), 251–257. https://doi.org/10.23675/sjlas.v35i4.155

Issue

Vol. 35 No. 4 (2008)

Section

Articles