The red patas monkey (Erythrocebus paras): An analysis of pathological changes and organ/body weight data in laboratory animals in a 12 year period

Abstract

The histopathology and body and organ weights have been evaluated for 76 adult red patas monkeys used as controls in routine short term toxicity studies.
Body and organ weights varied considerably, males weighting 2.45—7.7 kg and females 2.65—4.80 kg. Absolute organ weights did not exhibit a clear graphical relationship to body weight, although brain weight did show an exponential relationship when its weight relative to body weight was plotted against body weight.
Neoplastic changes were not seen in any male or female animal. Common lesions included sialodacroadenitis, sub-acute thyroiditis, chronic respiratory disease, interstitial nephritis and cystitis. Pulmonary and intestinal nematode infections were present in ten animals. It is concluded that the range of lesions identified resemble those present in many other species of laboratory animal maintained under conventional laboratory conditlons.