Ovarian hormones and pituitary responsiveness to gonadotrophin releasing hormone in mice

Authors

  • A A Gidley-Baird Department of Veterinary Physiology, University of Sydney
  • B M White Department of Veterinary Physiology, University of Sydney
  • F Dagnaes-Hansen Department of Pathology, Laboratory Animal Unit, Royal Veterinary and Agricultural University
  • J Hau Department of Pathology, Laboratory Animal Unit, Royal Veterinary and Agricultural University

DOI:

https://doi.org/10.23675/sjlas.v14i3.890

Abstract

In the present study the role of progesterone and oestradiol in modulating the responsiveness at the anterior pituitary gland to gonadotrophin releasing hormone (GN-RH) was investigated by measuring the release of luteinizing hormone (LH) in ovariectomised mice which had been pretreated with these steroids.
A significant release of LH was seen in the animals receiving GN-RH. Pretreatment with oestrogen and progesterone depressed LH levels in the animals which did not receive GN-RH, and resulted in a larger release of LH in the animals receiving GN-RH in comparison with the control group pretreated with oil.

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Published

01.12.1987

How to Cite

Gidley-Baird, A. A., White, B. M., Dagnaes-Hansen, F., & Hau, J. (1987). Ovarian hormones and pituitary responsiveness to gonadotrophin releasing hormone in mice. Scandinavian Journal of Laboratory Animal Science, 14(3). https://doi.org/10.23675/sjlas.v14i3.890

Issue

Vol. 14 No. 3 (1987)

Section

Articles